Highly active fluorogenic oxidase-mimicking NiO nanozymes

Section 1: Publication

Publication Type

Authorship

Li, D., Liu, B., Huang, P. J. J., Zhang, Z., & Liu, J.

Title

Highly active fluorogenic oxidase-mimicking NiO nanozymes

Year

2018

Publication Outlet

Chemical Communications, 54(88), 12519-12522

DOI

https://doi.org/10.1039/C8CC07062H

ISBN

ISSN

Citation

Li, D., Liu, B., Huang, P. J. J., Zhang, Z., & Liu, J. (2018). Highly active fluorogenic oxidase-mimicking NiO nanozymes. Chemical Communications, 54(88), 12519-12522. https://doi.org/10.1039/C8CC07062H

Abstract

Oxidase-mimicking nanozymes are attractive since they do not require H2O2, but such examples are quite rare. In particular, few can catalyze oxidation of fluorogenic substrates. We herein communicate that NiO nanoparticles are an oxidase nanozyme at physiological pH for fluorogenic Amplex red. Its activity is much higher than that of the commonly used nanoceria. This finding fills an urgent gap for biosensor development and intracellular imaging for the nanozyme field.

Plain Language Summary

Section 2: Additional Information

Program Affiliations

GWF: Global Water Futures

Project Affiliations

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Additional Information